Skate city rice lake12/25/2023 ![]() ![]() Known as transfer RNA, or tRNA, that molecule hauls around amino acids - the building blocks of every protein - in search of a blueprint that calls for its cargo. Wilson's team has now shown that one of those unconventional pathways involves modifying not the secreted protein itself, but the genetic code of a molecule that aids in its construction. After being constructed and folded into their near-final forms at the endoplasmic reticulum, they move on to the Golgi body, which packages and forwards them along to their ultimate destinations.īut certain proteins will bypass the Golgi body in favor of unconventional, poorly understood pathways. ![]() ![]() Most cellular machines, or proteins, are secreted in the same way. The results are published in Nature Microbiology. "The response I've gotten from people in my field is that they're very excited, because nobody's been able to get a handle on this," said Wilson. National Science Foundation-supported research from the University of Nebraska-Lincoln.Ī Nebraska team helmed by plant biologist Richard Wilson hopes that identifying an essential but formerly unknown stage in the fungal takeover of rice cells can accelerate the treatment or prevention of rice blast disease, which ruins up to 30% of global yields each year. The virulence of a rice-wrecking fungus - and deployment of ninja-like proteins that help it escape detection by muffling an immune system's alarm bells - relies on genetic decoding quirks that could prove central to stopping it, according to U.S. ![]()
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